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KMID : 1044320220240010026
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Annals of Clinical Neurophysiology
2022 Volume.24 No. 1 p.26 ~ p.29
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Lumbosacral polyradiculoneuropathy associated with combination therapy of nivolumab and ipilimumab
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Cho Eun-Bin
Kim Seung-Joo
Yang Tae-Won
Jung Seung-Uk
Jeong Hee-Jeong
Park Ki-Jong
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Abstract
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Immune checkpoint inhibitors (ICIs) have emerged as one of the most promising therapeutic options for advanced cancers. While ICIs have improved survival in multiple cancers, their increased use is restricted by various immune-related adverse events. In this report we describe a patient with renal cell carcinoma who received a combination of ICIs, nivolumab plus ipilimumab, and who developed lumbosacral polyradiculoneuropathy. Corticosteroid use was an effective treatment for this patient.
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KEYWORD
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Polyradiculoneuropathy, Drug-related side effects, Immune checkpoint inhibitors
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